New Method Update - Vitamin B Compounds in Food

Fitz Scientific
6 days ago
2 min read

Vitamin B Compounds in Food

The R&D Team at Fitz Scientific have created a highly sensitive method capable of detecting and quantifying Vitamin B compounds, using state‑of‑the‑art LC‑MS/MS technology.

The method has been validated across a wide range of matrices, including infant formula, adult nutritional’s, vitamin‑fortified foods, animal feed, beverages, and dietary supplements. The technique delivers exceptional precision and accuracy which are critical requirements for manufacturers operating in tightly controlled markets.

These capabilities will support manufacturers in meeting regulatory requirements across global markets while also providing enhanced quality assurance for product development and routine testing.

The new method is now part of Fitz Scientific’s expanding suite of advanced analytical services, supporting clients involved in nutrition, food science, and product formulation.

Below is a summary of the LOD levels and analytical ranges:

Calibration Range	Lower	Upper	Units	Measuring Range
Thiamine (B1)	0.001	0.05	mg/kg	LOD to 80mg/kg (extended by dilution)
Riboflavin (B2)	0.001	0.05	mg/kg	LOD to 80mg/kg (extended by dilution)
Niacin (B3)	0.002	0.01	mg/kg	LOD to 160mg/kg (extended by dilution)
Niacinamide (B3)	0.002	0.01	mg/kg	LOD to 160mg/kg (extended by dilution)
Pantothenic Acid (B5)	0.002	0.1	mg/kg	LOD to 160mg/kg (extended by dilution)
Pyridoxamine Dihydrochloride (B6)	0.0002	0.01	mg/kg	LOD to 80mg/kg (extended by dilution)
Pyridoxal Hydrochloride (B6)	0.0002	0.01	mg/kg	LOD to 80mg/kg (extended by dilution)
Pyridoxine Hydrochloride (B6)	0.001	0.05	mg/kg	LOD to 80mg/kg (extended by dilution)
Biotin (B7)	1	50	ug/kg	LOD to 80000ug/kg (extended by dilution)
Folic Acid (B9)	1	50	ug/kg	LOD to 80000ug/kg (extended by dilution)
Cyanocobalamin (B12)	0.04	2	ug/kg	LOD to 3200ug/kg (extended by dilution)